해외국 의약품을 직접 구입(직구)하거나 구입대행을 통해 구입하는 절차에서 소비자들은 약품의 품질 자체에만 관심하는 경향이 있다. 그러나 의약품이 생산된 나라에서 우리나라 집까지까지 도착하기하기 까지의 오래 걸리는 배송 절차 동안 약효과가 변질될 문제이 항상 존재합니다. 특히나 열와 습기 변동에 약한한 약품의 때에는 일반 택배송 방식으로 운송될 때 약효과가 줄거나 나쁜 재료이 만들어질될 수도 있습니다
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